The joint CSHA / NGF 2014 conference on “Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanisms, Novel Technologies”



The joint CSHA / NGF 2014 conference on “Nerve Growth Factor and Related Neurotrophic Factors: Emerging Concepts, New Mechanisms, Novel Technologies”
June 23-27, 2014, Suzhou, PR China,


Brain Projects
Mu-ming POO (ION, China)China’s Brain Project
Tadaharu TSUMOTO (RIKEN, Japan)Japan’s Brain Project
Marc-Oliver Gewaltig (EPFL, Switzerland)Europe’s Human Brain Project
Eve Marder (Brandeis, MA USA)*USA Brain Initiative
Bai LU (Tsinghua, China)A new way of working

Emerging concepts I – pro-fragment – expression, function, signaling
Barbara Hempstead (Weill Cornell Medical College)
Masami Kojima (AIST, Ikeda, Japan)

Emerging concepts II: Genetics and Epigenetics
Yi Sun (UCLA/Tongji Univ): Transcriptome analysis of spinal cord injury
José-Maria Frade (Cajal Institute, CSIC, Madrid) Tetraploidization & cognitive decline
in AD
M.J. During (Ohio State Univ, Columbus): The Brain Cancer Connection
Claes Wahlesdtedt Univ Miami*: Regulation of BDNF via Natural Antisense Transcripts

New mechanisms – signaling and function
Mart Saarma (Finland)  CDNF & Parkinsons’s disease
Nancy Ip (Hong Kong)TBA
Patrick Mehlen (France)TBA
Michael Sendtner (Germany)TBA
Carlos Ibanez (Karolinska & Singapore)TBA

HOT TOPICS
Seven selected from the abstracts submitted

Plasticity, Circuit, Behavior
Hailan Hu (ION Shanghai): Neural circuit mechanism of emotional and social behaviors
Sheng-Jia Zhang (Kavili Institute, Norway): Optogenetic dissection of entorhinal-
hippocampal functional connectivity
Minmin Luo (Beijing Institute of Biological Sciences): Neural circuits of reward and
stress behaviors
Keri Martinowich (Lieber Institute, Hopkins): Promoter specific mutations and
impact on circuitry, plasticity and behavior

Novel technologies
Fei Ann RAN (MIT & Harvard): CRISPR technologies
Weizhi Ji (CAS): Use of CRISPR-Cas9 to produce double mutant monkeys
Sunny Xie (Harvard): Live imaging of neurotransmitter release
Bianxiao Cui (Stanford): Neurotrophin trafficking at single molecule resolution
Hyun-Soo Je (Duke / Singapore)*: Activity-dependent synaptic competition

Blood brain barrier (BBB)
Angelina Angelova: Neurotrophin delivery using nanotechnology.
Robert Thorne: Neurotrophic factors as neurotherapeutics: the challenge of crossing or
bypassing the blood-brain barrier
Anirvan Ghosh*: Bispecific antibodies for delivery into the brain

SESSION 8    Neurological and psychiatric diseases
Dr Hiroshi Kunugi National Institute of Neurology and Psychiatry (Japan): BDNF &
Depression
Xiaoming Guan (GSK China): Neural repair strategy for neurodegenerative diseases
Maxime Cazorla (France): Small molecule TrkB antagonist/agonist
Christopher ROWE (Australia)*: Potential use of BDNF polymorphism for patient
stratification in AD clinical studies

*To be confirmed