Postdoctoral Position-Left-Right Neuronal Asymmetry by a Gap Junction Network in C. elegans

A postdoctoral position is available in the Chuang laboratory in the Division of Developmental Biology at Cincinnati Children's Research Foundation. We are interested in understanding the molecular mechanisms by which neurons differentiate and assemble into functional circuits, using the nematode Caenorhabditis elegans as an experimental organism (Chuang and Bargmann, Genes & Dev 2005; Chuang et. al., Cell 2007). The lab uses a multidisciplinary approach that ntegrates genetics, molecular biology, cell biology, biochemistry, electrophysiology and live imaging to address this question. To learn more about the lab, please visit.

http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/chuang/

http://neuroscience.uc.edu/faculty/person.cfm?NeuroID=180

This position involves the study of a gap junction network that coordinates left-right neuronal asymmetry. Prior experience in C. elegans is helpful but not a prerequisite. Applicants should have a Ph.D. degree (for less than three ears) in genetics, cell biology, molecular biology, neurobiology, biochemistry or similar with experience in molecular biology techniques. Interested candidates please send a brief cover letter describing research experience, CV, and names and contact information of three references to Dr. Chiou-Fen Chuang at
Chiou-Fen.Chuang@cchmc.org.

References:
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., and Bargmann, C. I. (2007). An innexin-dependent cell etwork establishes left-right neuronal asymmetry in C. elegans. Cell 129, 787-799.
(http://www.sciencedirect.com/
science?_ob=ArticleURL&_udi=B6WSN-4NRTWPR-P&_user=
2505525&_coverDate=05%2F18%2F2007&_rdoc=
1&_fmt=&_orig=search&_sort=d&view=c&_acct=
C000057658&_version=1&_urlVersion=0&_userid=
2505525&md5=45c38ac75b4cc63612526bd8f43cb002 )
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes & Dev. 19, 270-281.
(http://www.genesdev.org/cgi/content/full/19/2/270)