Cold Spring Harbor Asia Summer School Building and Mining Brain Cell Atlases and Connectomes

Cold Spring Harbor Asia Summer School

Building and Mining Brain Cell Atlases and Connectomes

Suzhou, China
June 26 – July 11, 2018

Course Description
An essential step in exploring brain function is to build a structural neuroanatomical framework with single cell resolution into which information spanning molecules, cells, circuits and systems can be registered, integrated and mined. This parallels the development of reference genome based frameworks for molecular data and promises to have a similar scientific impact. Challenges in mesoscale neuroanatomy and connectomics include cell labeling, sub-micron whole brain imaging, spatial registration and reconstruction, big data management and display, and computational analysis. Recent technological advances on multiple fronts are addressing these challenges. This intensive lecture and laboratory course aims to train a new generation of scientists to be equipped with multidisciplinary knowledge and state-of-the-art tools in structural neurobiology. The primary emphasis of the course will be on cell type specific, single-cell resolution brain-wide light microscopy and associated data analysis and circuit reconstruction in vertebrates. Students will learn the principles and practice of 1) genetic viral labeling of cell types and tissue clearing; 2) high throughput, high resolution light microscopy (including serial 2-photon tomography, light sheet microscopy, fluorescence micro-sectioning tomography, laser speckle imaging, etc); 3) image processing, atlas registration, neuron skeletonization and computational analysis using modern machine learning/AI tools 4) data management, interactive visualization and web dissemination ,the course will span multiple taxa including rodent, primates and zebrafish. The course will operate in the newly established Suzhou Institute for Brainsmatics, which is about one hour from Shanghai Hongqiao International Airport and 2 hours from PuDong International Airport.

Applicants should have a strong background in neuroscience or imaging/computation. In their personal statements, applicants should specify:
1) their experience with optical techniques,
2) how they will apply optical methods and mesoscale circuit anatomy in their current projects,
3) their long-term goals in learning more about brain connectomics.

Z. Josh Huang, Cold Spring Harbor Laboratory, USA
Qingming Luo, Huazhong University of Science and Technology, China
Giorgio Ascoli, George Mason University, USA
Partha Mitra, Cold Spring Harbor Laboratory, USA

Invited Lectures
Hongkui Zeng, Allen Institute for Brain Science, USA
Hongwei Dong, University of Southern California, USA
Michael Economo, Janelia/Howard Hughes Medical Institute, USA
Peter Strick, University of Pittsburgh, USA
Chris Xu, Cornell University, USA
Pavel Osten, Cold Spring Harbor Laboratory, USA
Hui Gong, Huazhong University of Science and Technology, China
Ann-shyn Chiang, National Tsing Hua University,Taiwan
Hermann Cuntz, Frankfurt Institute for Advanced Studies, Germany
David Kleinfeld, University of California San Diego, USA
Tianyi Mao, Vollum Institute/Oregon Health Science University, USA
Michael Miller, Johns Hopkins University, USA
Heping Cheng, Peking University, China
Angela Roberts, Cambridge University, UK
Min Gu, Royal Melbourne Institute of Technology, Australia

Regular Pricing
Course Location

The course will operate in the newly established HUST-Suzhou Institute of Brainsmatics (Chinese name: 華中科学技術大学蘇州脳空間信息研究院)
Address: 388 Ruoshui road, Huqiu district, Suzhou, Jiangsu 215004, China

Apply the course from Here:

Deadline: April 20, 2018