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Social Behavior

開催日 2014/9/12
時間 11:00 - 12:00
会場 Poster / Exhibition(Event Hall B)

Does being observed modulate self-conscious emotion in individuals with autism spectrum disorders?

  • P2-283
  • 守田 知代 / Tomoyo Morita:1,2 小坂 浩隆 / Hirotaka Kosaka:3,4,5 齋藤 大輔 / Daisuke N Saito:3,5 藤井 猛 / Takeshi Fujii:3,5,6 石飛 信 / Makoto Ishitobi:4,7 棟居 俊夫 / Toshio Munesue:8 猪原 敬介 / Keisuke Inohara:4 岡沢 秀彦 / Hidehiko Okazawa:3,5 柿木 隆介 / Ryusuke Kakigi:2 定藤 規弘 / Norihiro Sadato:5,9,10 
  • 1:大阪大院工 / Grad Sch of Eng, Osaka Univ, Osaka, Japan 2:生理研統合生理 / Dept of Integrative Physiol, NIPS, Aichi, Japan 3:福井大・子どものこころの発達研究センター / Res Center for Child Mental Dev, Univ of Fukui, Fukui, Japan 4:福井大医精神医 / Dept of Neuropsychiatry, Univ of Fukui, Fukui, Japan 5:福井大高エネ研 / Biomed Imag Res Center, Univ of Fukui, Fukui, Japan 6:国立精神・神経セ病院・精神科 / Dept of Psychiatry, NCNPH, Tokyo, Japan 7:国立精神・神経セ精神保健研 / National Institute of Mental Health, NCNP, Tokyo, Japan 8:金沢大・子どものこころの発達研究センター / Res Center for Child Mental Dev, Kanazawa Univ, Kanazawa, Japan 9:生理研大脳皮質機能 / Dept of Cereb Res, NIPS, Aichi, Japan 10:総研大院 / The Grad U 

When exposed to self-feedback images, individuals can experience negative social emotions (i.e., embarrassment). Our previous study of neurotypical individuals showed that being observed enhanced the extent of the embarrassment provoked by viewing self-face images, and induced a corresponding increase in activity in the right anterior insula (AI). It was recently proposed that the function of the AI to integrate diverse information and produce a subjective experience is impaired in individuals with autism spectrum disorders (ASD). To test this hypothesis, we measured the brain activity when 14 individuals with high-functioning ASD (mean age = 24.5 ± 6.7 years) and 16 neurotypical controls (mean age = 23.4 ± 3.4 years) viewed images of their own faces and those of others, in the presence or absence of an observer. In the control group, being observed significantly increased the extent of the embarrassment provoked by viewing self-face images, and the increase was correlated with an increase in self-related activity (SELF vs. OTHERS) of the right AI. By contrast, the ASD group did not show a significant increase in the extent of embarrassment, and the individual increase was not coupled with individual increase in self-related activity of the right AI. Being observed did not influence the subjective experience of emotion in individuals with ASD owing to atypical integrative processing in the right AI.

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