• Top page
  • Timetable
  • Per session
  • Per presentation
  • How to
  • Meeting Planner


Tsukahara Award Lectures

開催日 2014/9/11
時間 15:00 - 15:30
会場 Room A(Main Hall)
Chairperson(s) 中西 重忠 / Shigetada Nakanishi (大阪バイオサイエンス研究所 / Osaka Bioscience Institute)

Molecular and cellular basis for dendrite development and plasticity

  • AL-1-1
  • 榎本 和生 / Kazuo Emoto:1 
  • 1:東京大学大学院理学系研究科 / Graduate School of Science, The University of Tokyo 

Precise pattering of dendrites as well as axons is essential for correct wiring and function of neural circuits. In addition, dendrites from certain mature neurons change their shape in response to changes in the environment. We combine fly/mice genetics, imaging, and biochemical approaches to investigate the interplay between genetic and epigenetic control of dendrite morphogenesis in vivo, and deduce the functional importance of these regulatory systems in disease etiology. In particular, we focus our researches on the genetic and molecular regulation of dendrite pattering and plasticity in the Drosophila sensory circuits. In this talk, I first present how intrinsic and extrinsic cues instruct Drosophila sensory neurons to establish their unique dendritic fields on the body wall. In the latter part, I present two novel mechanisms, dendrite pruning and reshaping, that critically regulate dendrite plasticity in metamorphosis.

Copyright © Neuroscience2014. All Right Reserved.